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AETIOLOGY AND EPIDEMIOLOGY The term "Lyme disease" is derived from the name of a small town in Connecticut, Old Lyme, where, in 1975, numerous cases of arthritis of suspected infectious origin were detected in the majority of both the adult and paediatric population. The disease has also been described in the European literature since quite some time.
Chlorambucil belongs to the class of alkylating agents (nitrogen mustards) and has both cytotoxic and immunosuppressive effects.   CHEMICAL STRUCTURE AND PHARMACOKINETIC PROPERTIES Following oral administration, chlorambucil is rapidly absorbed from the gastrointestinal tract by passive diffusion, particularly if the patient is fasting. It is metabolised by the microsomal system in the liver....
The anticoagulant solutions used in veterinary transfusion practice normally contain citrate (which prevents blood clotting through the chelation of calcium), dextrose (which preserves the glycolytic energy metabolism of the red blood cells), phosphate and adenine. During the storage of blood in bags, the concentration of 2,3 diphosphoglycerate (2,3 DPG) gradually decreases. 2,3 DPG reduces the...
Feline herpesvirus type1 (FHV-1) is the causative agent of feline viral rhinotracheitis, an infective and contagious disease characterised by respiratory symptomology and often complicated by the simultaneous presence of other pathogens associated with the respiratory diseases complex in the cat (URTD: Upper Respiratory Tract Disease) such as feline Calicivirus (FCV), Chlamydophila felis and...
Otodectic mange or otoacariasis is a parasitic infestation of the external auditory canal caused by Otodectes cynotis, a cosmopolitan psoroptid mite with an oval body about 460-530 µm long and a long, conical rostrum. The limbs are long and terminate with foot-like structures which, at their extremity, have a cup-shaped suction pad (pulvillus) which the parasite uses to move rapidly between...
Angiostrongylus vasorum, commonly known as the French heartworm, is a metastrongylid nematode that causes canine cardiopulmonary angiostrongylosis. The parasite, in its adult stage, localises to the right ventricle and pulmonary artery of the definitive host (dog, fox and occasionally wolf, coyote and ferret) causing clinical pictures of variable severity, but often fatal. The biological life...
The term glaucoma refers to a group of neurodegenerative diseases that can affect the dog and the catcharacterized by polymorphic clinical symptoms having as a common denominator an increase in the intraocular pressure (IOP); this may trigger a chain of events first in the optic nerve and secondly in the retina, causing a damage to the integrity and function of these ocular structures which may...

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